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  • Currently 3.49/5
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Rating: 3.49/5 (176 votes cast) | View All 53 Reviews

Prime (150 caps)

By: USPlabs

Price: $83.99$47.36

Availability: Currently Out Of Stock


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USP Labs Prime: The Ultimate Muscle Pill!

How does USPLabs Prime work?

This is an interesting question. Because we found no evidence for androgenic activity, we believe it to have anti-glucocorticoid effects, providing a possible mechanism for the increase muscle mass seen with USPLabs Prime. It may also be something related to improved nutrient absorption or utilization. In fact, the recomposition effects - even on subjects who were making poor food choices and consuming 750-1000kc/cal surplus per day – are downright amazing. It's not something recommended, but when testers are pounding buffalo wings and pizza while putting on massive size and strength – AND getting leaner – you can't help but take notice.

What can I expect to experience when taking USPLabs Prime?

  • Permanent Muscle Gains
  • Does not cause shut-down or suppression!
  • Promotes Muscle Gain of Thick, Dense Variety!
  • Extremely Potent Re-composition Effects
  • Enormous Strength Gains
  • Incredible Recovery Speed
  • All-Day Muscle Fullness/Hardness
  • Train harder and longer than you ever have
  • Incredible Euphoria
  • Safe to use in competition

Obviously, everyone loves the effects of androgenic-myotropic substances such as pro-hormones, pro-steroids (the select few that work). They allow you to gain muscle and strength, while losing fat. Unfortunately, they also come with a set of drawbacks, including prostate issues, gynecomastia, cardiovascular problems and one that many are likely very familiar with – Testosterone suppression & post cycle therapy (PCT). Every time you stop using such androgenic-myotropic substances, you are invariably required to take a number of other products designed to help your body recover endogenous testosterone production. If you don't, you'll lose the muscle and strength you've gained and gain back the fat. In fact, you'll end up right back where you started or worse.

What you need is something that is highly myotropic, yet doesn't suppress testosterone production. Sounds easy; yet such compounds are rarer than a 1903 T3 Honus Wagner (for all you baseball card collectors out there). By now, you expect USPlabs to deliver unique products and formulations others simply cannot.

We have, in fact, found a formula which produces significant muscle building activity in humans without hormonal suppression!

In our own pilot study, a group of 12 exercising men were found to experience the following, on average, over a 30-day period while using USPLabs Prime:

  • 4.29 lbs increase in body weight
  • 6.37 lbs increase in lean body mass
  • 2.08 lbs decrease in fat mass
  • 40.83 lbs increase in bench press strength (3 RM)
  • 54.58 lbs increase in squat strength (3 RM)

How long until USPLabs Prime starts to work?

Most have noticed increased workout production and overall body hardening within a few days. However, everyone agrees by the end of week 3 USPLabs Prime is in full force – running through your veins and demonstrating the unique muscle enhancing effects only it can!
Here's a timeline based upon user feedback:

Week 1

You will begin to experience the power of USPLabs Prime during your workouts. Weight will begin to feel lighter than normal and you'll begin to have great workout after great workout - even on days you don't necessarily enter the gym with the highest amount of intensity or energy. You will find the ability to summons strength almost at will. You also may begin to notice the muscle building effects kicking in where you're whole body will begin to harden.

Week 2

You'll continue to have awesome workouts. During these workouts you'll begin to feel an intense full-body muscle fullness and hardness. While it's a pump per say, it's very unique and unlike that from creatine, NO or other products. In addition, the super-human recovery abilities will begin to kick in. Remember, some pro athletes use Pharmaceuticals to significantly increase recovery so they can train harder, longer & more frequently. USPLabs Prime significantly speeds the muscle repair process, leading increase training intensity, volume & frequency.

Week 3

This is the magical week our subjects cannot stop talking about. For most, by the end of Week 3 is when USPLabs Prime REALLY begins to impart its force upon your body. You'll fly through your workouts, your body will be hard as a freakin rock – all day long.

Week 4

The great thing about USPLabs Prime is it just continues to get better and better the longer you use it. During week 4 is where you'll begin to set personal records frequently. Weights that were heavy in the past are going up like butter – and you feel like THE MAN. By this point you should be getting plenty of compliments from those around you noticing you're -bigger- and -stronger-. And don't be surprised that your body is in such a myotropic state that you get a chest pump when you're squatting!

Week 6 and Beyond

At this point you should have put on some serious, REAL muscle mass. It will be thick and dense, not simply water weight. Some subjects have even noted their asthetics have changed and they now have a V-taper that they've never had before. And, this may be very hard to believe – but many users have reported that after taking USPLabs Prime, their bodies have permanently changed. They have more muscle (thick and dense) with a more athletic build. Now, we're not saying that is going to happen to you, but many of our tests subjects are reporting this.

Do I need to Cycle USPLabs Prime?

Well, you won't want to come off! And since it does not statistically affect hormonal levels one way or another, you can stay on for long periods. But, just to be safe, we suggest 12 weeks on, 4 weeks off. Or at least two, 3 week breaks per year.

Does it have any side effects?

People are training so intense and heavy and gaining muscle & strength at such a rapid pace, that the Central Nervous system cannot keep up. So that is why we recommend using USPLabs Prime on a 5 days on, 2 days off schedule. Certainly, it can be used every day, just take this as fair warning if you end up crushing your CNS because you're training balls-to-the-wall everyday! You will be training as such a heightening level, both mentally and physically, you just have to monitor yourself.

Can I stack USPLabs Prime with any other supplements?

The ultimate stack is ALWAYS going to include Anabolic-Pump due to it's ability to increase the effectiveness of every supplement you take & properly utilize your food intake – which is critical to any plan – even steroids. In addition, adding PowerFULL to the mix forms what we believe to be the greatest stack ever assembled.

USPLabs Prime contains two extremely potent, novel ingredients:

Tribulus Aquaticus

Tribulus Aquaticus is a rare species of herb in the same family as Tribulus Terrestris. However, once you try USPLabs Prime you'll soon realize the comparisons stop there. The steroidal glycosides contained in USPLabs Prime make the saponins of tribulous terrestris look like the placebo!

Steroidal Gylcosides

Tribulus Aquaticus contains active steroidal components called steroidal glycosides. However, the components in USPLabs Prime are unique to our specific extract of Tribulus Aquaticus and have not been found in any other compound in the world. These steroidal glycosides are believed to exert their muscle growth effects through non androgen receptor-mediated mechanisms, perhaps by possessing anti-glucocorticoid activity similar to pharmaceutical compounds such as methandrostenolone (D-bol). In any case, it's obvious that these steroidal glycosides allow for a retention of nitrogen and either a decline in the catabolic processes related to skeletal muscle or an improvement in protein synthesis; the end result of which is increased muscle mass.

CellMend – King Of Medicines

The Ayurvedic medicinal system points to a wonder-fruit called terminalia chebula. Its viewed as one of the most potent CNS and body adaptagenic compounds the world has ever seen. It's proposed that terminalla chebula balances the entire body mentally and physically - placing your body in a perfect state of balance during times of intense stress. Terminalia Chebula is called the -King of Medicines-. It's always listed first in the Ayurvedic meteria medica because of its extraordinary powers of healing. According to Charak, the most eminent Ayurvedic physician, Terminalia Chebula is the best fruit for rejuvenation and disease cure.

Additional Terminalia Chebula benefits:

  • Also contains antioxidant components, which indicates it may increase the life of tissues.
  • In Ayurveda, Terminalia Chebula is used for 'Srotoshodhana' or purifying the channels of body
  • It's thought to stimulate & protect the liver.
  • When taken with meals, it's believed to sharpen the intellect, increases strength, stimulates the senses, expel urine, stool and other waste materials from the body.
  • It's used in nervous weakness & irritability. It promotes the receiving power of the five senses.
  • Based on its comprehensive properties, it promotes appetite and helps indigestion.

A Better Way?

You see, there are tens of thousands of natural herbs found around the world...

And, wouldn't it make sense that some of these herbs would work with your body - not against it - to help your efforts in the gym? Of course it would...

While many companies have tried in the past and failed, USPlabs has quickly garnered a reputation for producing effective products that are based off herbs.

"When dealing with herbals, it's ALL about the quality of the herb & the extract. Get the extract wrong or use a cheap version and you might as well be swallowing dirt!" says USPlabs CEO Jacob Geissler

Since its release in late 2008, USPlabs natural anabolic support named "USPlabs Prime®" has been a God-send for those looking for results...*

"People wanted a natural product that could help their efforts. We spent a great deal of time & money to ensure we got USPlabs Prime® right!" said Geissler

And get it right we did. Users swear by USPlabs Prime® & that's why it's quickly become a hot seller & has been voted #1 Platinum Non-Hormonal Anabolic Agent.*

P.S. To truly maximize the result of any supplement, you must combine with proper nutrition & exercise plans. Feel free to visit our forums (link at top of this page) for information.

Cellmend Research

Oxidative Stress and Lipid Peroxidation are recently being implicated in a wide-range of physiological disorders, due to their damaging effects on cell transcription and homeostasis. Oxidative Stress is the production of Reactive Oxygen Species (ROS) such as peroxides and free radicals, as a result of an imbalance in cellular reduction – that is, as the mitochondria metabolize energy, they undergo cellular respiration; this process produces ‘reactive oxygen', and damaging reactive oxygen species arise when the body cannot readily detoxify the intermediates in this process. Oxidative Stress then ensues when the body cannot repair the stress from the initial reaction, or as mentioned, readily redox the productive aspect of cellular respiration. The tangible effects of OS are inhibited DNA and protein transcription, membrane instability, aptosis, or ultimately, necrosis. Such conditions play a prominent role in degradative neural diseases such as Parkinson's and Alzheimer's.

Lipid Peroxidation (LP) is a highly similar process, and involves the degradative oxidation of cell plasma membranes (as cell membranes are comprised almost entirely of lipid strains).

Ultimately, LP results in cell membrane instability, and acute cellular damage. It is also implicated in a wide-range of physiological disorders. As a result of these damaging processes, much research is being conducted in the field of anti-oxidants – or, compounds which combat the oxidative stresses of cellular respiration and free radical production. Recent research has revealed Terminalia Chebula (TC) has both potent secondary and direct effects on oxidative stress. TC has also been shown to mitigate hepatic oxidative stress, via its aforementioned anti-oxidative and membrane stabilizing capacities.

Prime References:

-Fabricant DS, Farnsworth NR. The value of plants used in traditional medicine for drug discovery. Environ Health Perspect. 2001 Mar;109Suppl 1:69-75.
-Vuorelaa P, Leinonenb M, Saikkuc P, et al. Natural products in the process of finding new drug candidates. Curr Med Chem. 2004 Jun;11(11):1375-89.

*Planet Muscle Magazine - March/April 2009

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Customer Reviews for Prime by USPlabs

Write a review and share your thoughts with other customers.

View All 53 Reviews For Prime

  • Currently 2/5
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Review posted on: 2009-03-19 02:01:42 -0400

Well finally at around week three I started to feel a bit more pumped in and out of the gym, but it never really went beyond that. I did seem to get slightly leaner also, but no other amazing effects, like many have stated in the reviews. As of writing this I am on week seven and the mild positive effects faded after week six (I'm dosing 6 caps seven days per week). It's too bad, I had hoped to not use prohormones any longer, but honestly, I crave a real pump and the all day muscle fullness that comes from them. Maybe one day a company will come out with a natural product that actually delivers. If Prime was cheap as hell, I would throw it in with other stuff once in a while, but it is sooo not worth the cost...but hey maybe it'll work for you.

  • Currently 3/5
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Good product By: Levente

Review posted on: 2009-03-08 06:55:39 -0400

Dont expect any miracle from this. You will feel better because of the adaptogen properties of Terminalia Chebula. Ginseng and royal jelly would do the same thing for 5$. The increased hunger and the ability to work out longer will indirectly help you get more muscle, but it is overpriced in my opinion.

  • Currently 5/5
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Stuff works By: Henry

Review posted on: 2008-12-20 00:10:55 -0500

thats the bottom line, it works for me big time and everyone who I've recommended it to. Word to the wise, don't screw around with the 5 on 2 off, take it everyday. 5 on 2 off is for wussies. I don't see many people talking about this, but if you take 3 Prime about 3 minutes before you out! Strength and aggression is through the roof. I've been doing this since it came out and had to train a few times without it (was traveling,forgot pills you know) and my workouts sucked. Not sure if it was mental or what. I started stacking with Jacked and WWHHOOAA, good stuff. Some of my juicehead buddies are taking Prime during PCT and making strength gains, they are shocked. Keep the crazy formulations coming USP as my body is loving them!

  • Currently 5/5
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WOW By: Lance

Review posted on: 2008-11-29 12:43:56 -0500

Very impressed by Prime. Yeah I gained muscle (9 pounds in 8 weeks), lost bodyfat (3 pounds in 8 weeks) and strength (45 on bench, 55 on squat, 40 on DL) but what really does it for me is the recovery. I train super high volume (only way I can grow) and currently doing updated version of German Volume Training. Typically I overtrain after 4-6 weeks and begin to feel lethargic. Prime allows me to train harder, for longer and feel good enough to come back teh next day. I also play semi-pro football and have noticed my recovery time between practies and games is at an all-time high...and I'm 31 so I'm an old man in this football game! I plan to stay on for the entire season as I have no side effects or shutdown. I'm very impressed this is a natural product. I would gladly pay twice the cost.

  • Currently 5/5
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Dude, it's awesome! By: Tommy

Review posted on: 2008-11-28 13:48:24 -0500

Loving this stuff. Ran Prime for 6 weeks (9 caps for first ten days, then 6 caps a day) and gained 11 pounds and actually dropped a little bit of bodyfat. So lean mass gain was 12-13 pounds. Pretty impressive, especially since I didn't have any side effects except if I took it with my pre-bed protein shake I had trouble falling aslepp. But as long as I took it before then, I was fine. Strength gains were stupid...went from 285 for 6 on the squat to 325 for 8! Bench went from 255 for 5 to 315 for 6! Pullups went from 30 pound for 6 to 65 pounds for 5. I didn't really believe the permanent gains were true because I've done pro-hormones & designers before and always losyt most of my gains even when I did proper PCT, but its true. here I am 4 weeks after stopping Prime and I have actually gained 2 more pounds (bodyfat the same) and my strength is still going up. Seems to have some residual effect. Needless to say these results are WAY more than i expected so of course I'm thrilled. Good stuff!

View All 53 Reviews »

Prime Supplement Facts

Serving Size: 3 capsules
Servings per Container: 50

  Amount Per Serving % Daily Value
Proprietary Blend:
(Tribulus Aquaticus (Stem and Leaf) Extract, Chebulic Myrobalan (Bean) Extract)
2400mg **

* Percent Daily Values are based on a 2000 calorie diet.
** Percent Daily Values not established.

OTHER INGREDIENTS:  Gelatin, Corn Starch, Magnesium Stearate, Yellow 5, Blue 1, Titanium Dioxide Color

Prime Directions:

Take 3 capsules twice a day with food. Take on a 6 days on, 1 day off schedule.


This product is only intended to be consumed by healthy adults 18 years of age or older. Pregnant or nursing women should not use this product. Consult with your health care provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAO-B inhibitor or any other medication. Discontinue use and immediately consult your health care professional if you experience any adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing. KEEP OUT OF REACH OF CHILDREN.