Developed To Cause Extreme Body Fat Loss While Sparing Muscle Tissue!
Naturally Occurring Metabolic Regulator is a powerful, patent pending, non stimulating dietary supplement developed to cause extreme body fat loss while sparing muscle tissue. When used as directed Dicana has the ability to raise your Resting Metabolic Rate (RMR, the rate at which your body burns calories at rest) and can dramatically shift the proportion between lean body mass and adipose tissue (fat) in favor of lean body mass. Dicana works by increasing protein synthesis thru calorie repartitioning while simultaneously causing an increase in body temperature and oxygen consumption for extreme fat loss without muscle catabolism.
In the world of fat burning physiology, Dicana exerts a truly unique phenomenon, there is certainly NOTHING in today's marketplace that even comes remotely close to the powerful metabolic activity of Dicana.
You see, not only is Dicana metabolically active on its own but Dicana also has direct reversible pathways to T3, Tricana (tiratricol) and T2 and therefore acts as a precursor to these powerful fat shredding compounds. I guess you could say that Dicana is like 4 powerful fat burning supplements in one.
Dicana is a not central nervous system stimulant and thus will not give you the jitters. Enhanced results may be accomplished with a healthy diet high in protein and proper anaerobic training. Dicana? is truly a revolutionary fat loss product and the quintessential supplement for anyone concerned with weight management or enhanced body composition.
There is no other product on the market that can make these claims and there is no other product on the market nearly as effective as the fat incinerator Dicana. No other company can sell you Dicana, because after we discovered this metabolite and its unique metabolic activity we filed a U.S. utility patent in order keep the competition from stealing our intellectual property.
Pick up a bottle of Dicana today and see for yourself, that lean, fat free body you always wanted can finally be yours!
Here are the straight facts:
DICANA
Diiodothyroacetic acid is a direct naturally occurring metabolite of T3, Triac, and T2, (1,2,3) which was never investigated or used as a fat loss aid before ThermoLife introduced Dicana. Diiodothyronines and their metabolites, like DIAC, retain the calorigenic and antilipidemic effects of thyroid analogues (4,5). Diiodothyroacetic acid in particular has been found to have very strong effects in lowering "bad" LDL cholesterol and reducing blood lipid peroxidation(6). One of the prime concerns regarding using thyroid mimetics to promote fat loss is the danger of thyroid suppression. However it has been identified that only the 3,5 analogues of diiodothyronines (and thus their metabolites which retain the same key structure-activity characteristics regarding thyroidomimetic action) and not their 3,3' isomers suppress TSH levels, leading to hypothyreodism(7). The new version Dicana contains only the 3,3' isomer of diiodothyroacetic acid, thus minimizing thyroid suppression fears.
GINGER
Ginger is a popular herb and spice with many traditional medicinal applications. Of interest in the making of Dicana was it's energizing and antiobesity effects. It is important to maintain energy levels during Dicana assisted fat loss cycles, since lowering calories, increasing exercise and enhancing base metabolism work to deplete energy levels. Adding stimulants like caffeine might be easy, but it was not a good option since thyreodomimetics should not be stacked with stimulants due to increased chance of side effects. Also many people do not enjoy using stimulants or are very sensitive to them. Thus ginger was picked for its well known tonic effects, lacking the drawbakcs of stimulants. Of prime interest are also the antiobesity effects of ginger which are two-fold: First, ginger increases basal temperature oxygen consumption and metabolic rate(8,9,10,11), due to the capacity of it's components to stimulate the vallionoid receptor subtype 1 (TPRV-1). Also ginger can inhibit the intestinal absorption of dietary fat by inhibiting it's hydrolisis, acting as a pancreatic lipase inhibitor(12).
FORSKOLIN
Forskolin is a labdane diterpene with the capacity to mimick the effect of TSH on the thyroid, increasing cAMP concentrations and thus stimulating thyroidal hormones production.(13). Thus it both works synergistically with Diac to enhance thyroid-induced metabolism and minimizes any slight chance of thyroid supression. Forskolin also has the capacity to increase lipolisis at the adipocyte level (14). The effectiveness of forskolin in lowering fat while promoting lean body mass has been well established in men (15).
References:
1. Endocrinology. 1990 Oct;127(4):1617-24.Links Identification of 3,3'-diiodothyroacetic acid sulfate: a major metabolite of 3,3',5-triiodothyronine in propylthiouracil-treated rats. Rutgers M, Heusdens FA, Bonthuis F, Rooda SJ, Visser TJ. Department of Internal Medicine, Erasmus University Medical School, Rotterdam, The Netherlands.
2. Endocrinology. 1989 Jul;125(1):433-43.Links Metabolism of triiodothyroacetic acid (TA3) in rat liver. II. Deiodination and conjugation of TA3 by rat hepatocytes and in rats in vivo. Rutgers M, Heusdens FA, Bonthuis F, Visser TJ. Department of Internal Medicine I, Erasmus University Medical School, Rotterdam, The Netherlands
3. Metabolic pathways of tetraiodothyroacetic acid, triiodothyroacetic acid, tetraiodothyropropionic acid and triiodothyropropionic acid EUNICE V. FLOCK, JESSE L. BOLLMAN and GEORGE H. C. STOBIE Mayo Clinic and Mayo Foundation, Rochester, Minn., U.S.A.
4. Thyroid hormone analogs for treatment of hypercholesterolemia and heart failure: past, present and future prospects Eugene Morkin a,*, Paul Ladenson b, Steven Goldman a,c, Cynthia Adamson a
5. The immediate action of L-thyroxine, L-tetraiodothyroacetic acid, diiodothyronine, diiodothyroacetic acid and L-thyronine on oxygen consumption and body temperature in the hypophysectomized rat; the action of cortisone.
6. Effects of iodotyrosines, thyronines, iodothyroacetic acids and thyromimetic analogues on in vitro copper-induced oxidation of low-density lipoproteins. Chomard P, Seguin C, Loireau A, Autissier N, Artur Y. Unit? de Biochimie Pharmacologique, UFR des Sciences Pharmaceutiques et Biologiques, Dijon, France.
7. Effect of 3,5-diiodo-L-thyronine on thyroid stimulating hormone and growth hormone serum levels in hypothyroid rats. Moreno M, Lombardi A, Lombardi P, Goglia F, Lanni A. Dipartimento di Chimica, Facolt? di Scienze, Universit? degli Studi di Salerno, Italy.
8. Pungent principles of ginger (Zingiber officinale) are thermogenic in the perfused rat hindlimb. Eldershaw TP, Colquhoun EQ, Dora KA, Peng ZC, Clark MG. Department of Biochemistry, Faculty of Medicine, University of Tasmania, Hobart, Australia.
9. Hum Nutr Clin Nutr. 1987 Jan;41(1):89-92.Links Effect of ginger on metabolic rate. Henry CJ, Piggott SM.
10. Pflege Aktuell. 2005 Apr;59:255.Links [Ginger gives warmth] Vef-Georg G.Pflege- und Heil- pflanzenfachfrau Lehrerin f?r Pflegeberufe und Buchautorin.
11. Physiol Behav. 2006 Aug 30;89(1):85-91. Epub 2006 Mar Metabolic effects of spices, teas, and caffeine. Westerterp-Plantenga M, Diepvens K, Joosen AM, B?rub?-Parent S, Tremblay A. Department of Human Biology, Nutrim, Maastricht University, Maastricht, The Netherlands. m.westerterp@hb.unimaas.nl
12. Antiobesity actions of Zingiber officinale Roscoe Han LK, Gong XJ, Kawano S, Saito M, Kimura Y, Okuda H.
13. Forskolin stimulation of thyroid secretion of T4 and T3. Laurberg P.
14. Forskolin as an activator of cyclic AMP accumulation and lipolysis in rat adipocytes I Litosch, TH Hudson, I Mills, SY Li and JN Fain
15. Obes Res. 2005 Aug;13(8):1335-43. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Godard MP, Johnson BA, Richmond SR. University of Kansas, Department of Health, Sport and Exercise Sciences, Applied Physiology Laboratory, Lawrence, KS 66045, USA. mgodard@ku.edu
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Directions:
As an adult dietary supplement take 1 capsule 1-3 times daily. After 6-weeks of continual use, a 2-3 week cessation period is recommended.
WARNING:
Do not take if you are pregnant, nursing or considering pregnancy. Not to be taken by children or the elderly. Do not take if you have any medical condition, especially thyrotoxicosis, cardiovascular disorders (including angina, coronary artery disease and hypertension), diabetes mellitus, diabetes insipidus or adrenal cortical insufficiency. Consult your physician prior to use if you are taking any medication including Anticoagulants, Sympathomimetic agents, or Thyroid drugs. Discontinue use immediately if yopu experience fatigue, lethargy, or severe diarrhea. KEEP OUT OF REACH OF CHILDREN.
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