AndroMass (168 softgels)

AndroMass: Super-1-DHEA & Super-4-DHEA!

Product Highlights:

• Body Remodeling. Build size, strength and power.
• The Real Deal. AndroMass delivers the muscle building power of 428mg/week of injectable testosterone. That’s serious.
• Guaranteed Absorption. No needles, no creams, no liver stress - yet we are achieving the highest bioavailability of any oral steroid available in the world.
• The Birth of AndroSeries. How did we come up with such an effective, safe and legal product?

How does AndroMass compare?
Standard Capsules or Tablets Methylated pro-hormones, designer steriods, and pro-steroids (1)
Benefits:
Not equivalent or Not calculated	Equals Muscle Building Effect of Injectable Testosterone 428mg/week Testosterone Enanthate
Fast acting, but likely to leave long acting metabolites	Fast Acting / Fast Clearing Maximum blood levels within 3 hours
Insufficient androgenic potency may cause libido loss and gyno	9:7 Balanced Myotropic : Androgenic
Not a good standalone / Limited stackability with other methyls	Standalone or Stackable Solid hormonal base
Erratic unreliable absorption2	Reliable Oral Delivery Non-food dependent
May decrease appetite from liver stress	Appetite Supporting Maintains hunger to support growth
Unnatural – chemically modified structure has toxic effects	Naturally Occurring Steroids Zero toxicity
Side-Effects:
Liver toxic	Liver Safe Non-toxic
Increased chance of contracting on-cycle and post-cycle gyno	Minimal Gyno Risk Minimal estrogen/SHBG disruption
Excessive disruption of cholesterol levels	Minimal Cardiovascular Risk Minimal effect on HDL/LDL
Suppresses libido, erection hardness and penis sensitivity	Minimal Libido Reduction Minimal effect on erections & sexual desire
May cause nausea or sickness	Non-Toxic No sickness
Not safe for long-term use	Safe for TRT Long-term safety
Quality & Support:
Steroids are likely to be untested	100% Purity & Identity Steroids verified by LC-MS & NMR from a 3rd party lab
Not likely	24/7 Chat, Email or Phone Support Live Product Specialists
Not likely	150% Money Back Guarantee3 Results Guaranteed
Not compliant	DSHEA compliant Legal to sell as a Dietary Supplement

Don’t Buy AndroMass Until You Read This:

Several months ago I was considering an extended cycle of AndroMass to help get me back in shape. I hadn’t lifted in months, my diet was weak and I was probably in the worst shape of my life. Then I had a strange feeling…

I realized -- I’m not good enough for AndroMass.

Steroids are like nitrous. You should build a solid engine before you inject it with nitrous – or else you could do some serious damage. I came to the realization that my body lacked a solid foundation. It became clear – I was not ready for AndroMass.

Are You Ready?

Getting big means pulling out the big guns – heavy weight, heavy food, and heavy rest. And this means you better have your body structure ready to pack on the muscle.

If you are out of shape, then here is some advice – Train naturally for a few months and invest time into getting your “foundation” developed. In a nut shell, do the following –

• Stick to “compound” multi-joint exercises (push/pull type work)
• Strengthen your weakest areas
• Perform different exercises each workout
• Use free weights – not machines

Hopefully this information was just a reminder for you – if not, you’ve got a lot of research to do before you jump on a product of this magnitude. Spend some time learning and come back in several months.

For those that are ready, continue on to the fun stuff…

Getting Your Ass Kicked

If you’ve used any of the “designer steroids” on the market, you are probably familiar with the compound Superdrol. The toxicity of this compound is so extreme that it makes you sick, nauseated and unable to eat within 3-4 weeks – thus having limiting utility in a bulking cycle. It also causes excessive hypertension which leads to migraines and nose bleeds. (1-3)

Superdrol is a super steroid for sure, but it’s not a super pleasant experience – and it has left a demand in the bodybuilding industry for a product that delivers the same level of power, without the disabling side-effects.

Before I tell you what we decided to do, let’s take a quick trip down memory lane…

The Good ol’ Days

It wasn’t long ago when you could walk into a local vitamin store, and buy a nice big bottle of steroids.

From 1998 to 2004 the health industry saw the biggest surge in steroid usage in the history of mankind. Everybody and their uncle were using some kind of steroid, and probably not even realizing it until the ban in 2004.

Back then the most popular products where 4-AD (4-androstenediol) and 1-AD (1-androstenediol/dione).

Since both compounds were naturally occurring and non-methylated there was virtually zero liver damage, kidney stress, or risk of gyno. (11, 12)

4-AD was like testosterone’s little brother. It was well known for producing very respectable gains in lean muscle with minimal side effects. Since 4-AD converted to estrogen, it was often stacked and well balanced with the non-estrogenic 1-AD. This was the most popular, effective and safest stack ever created for building mass.

We took what we knew would work and found the closest legal compounds –

• 3b-enanthoxyandrost-1-en-17-one (Super-1-DHEA)

• 3b-enanthoxyandrost-4-en-17-one (Super-4-DHEA)

Super cool -- both of these compounds are only one step away from the good ol’ pre-2004 steroids. (4-6)

New Rules – Same Game

Things have changed a bit since 2004 – especially the prices of steroid hormones.

Because of the high materials costs we had to design a more efficient way of delivering these compounds – so we maximized our delivery technology and created a new liquid delivery system that is now achieving near injection efficiency at 85% absorption and 75% bioavailability. It’s called Liqua-Vade Hormone Transport Complex (HTC). Watch how it works >>>

Despite the challenges, nothing was compromised.

We still included a massive dose of steroid into each softgel in addition to the increased delivery – With this, we believe we’ve created the greatest steroid formula in the world. I talked about that here >>>

Let’s just say AndroMass is easily safer, stronger and smarter than its predecessors. In the ring with the former heavy weights, AndroMass can hold its own.

Why Does It Feel Like The Real Thing?

AndroMass feels like injectable testosterone, because it practically is injectable testosterone.

When considering the dose and bioavailability for AndroMass we spent an intensive 300+ man hours calculating the proper dose to match the effectiveness of injectable steroids. Since most safe and effective steroid cycles are built around 400-500mg/week of injectable testosterone – we figured that was a good target.

The standard dose of AndroMass is equivalent to the muscle building potency of 428mg/week of injectable testosterone enanthate.

Expansion of the MusclesIntra-Cellular Swelling

One of the most important and immediate muscle building effects of steroids is their ability to increase kidney production of erythropoietin (EPO). This is the hormone that directly signals blood cell production from bone marrow. (7)

This action increases total blood volume relatively quickly and is responsible for “the pump” often noticed after 1-2 weeks on a steroid cycle. It plays an important role in hypertrophy as well, by engorging the muscles in nutrient rich blood and delivering more glucose for an increased physical working capacity.

The increase in blood cell production will occur fairly rapidly with AndroMass – likely to be noticed within the first week.

Splitting of the Muscle Cells

The active steroids in AndroMass will increase GH and IGF-1 production – and they are key players in the creation of new muscle cells – known as hyperplasia. (8-10)

Hyperplasia is known as the more permanent effects seen from steroids. This effect reshapes the physique beyond the temporary swelling of muscle cell size. (8-10)

Another key requirement for the formation of new muscle tissue is sufficient nuclei concentration within the muscle cells. Steroids are known to increase the number of nuclei in response to training.(10)

Permanent Effects     

Both the increase in red blood cells and nuclei have been shown to stay intact, even after many months or years after the steroids or physical training have been discontinued. (7) This means that the muscular enhancement obtained from steroids is partially permanent.Permanent Muscle Growth

The increased nuclei protect from under-training, allowing muscle to stay intact during extended periods of inactivity. Nuclei protect inactive muscle tissue from degradation and shrinkage.

Building the Ultimate Stack

As we intended, all of the AndroSeries products are safe to stack with each other depending on the gains you desire.

AndroMass is a great low-bloat mass builder – and will produce gains similar a testosterone and boldenone stack. If you are looking to further enhance vascularity and muscle fullness, then AndroHard would stack well.

On the other hand, if you are sensitive to androgenic related hair loss then AndroLean will have much lower androgenic potency – while keeping gains lean and tight.

References:

1. Methasteron-associated cholestatic liver injury: clinicopathologic findings in 5 cases.

Shah NL, Zacharias I, Khettry U, Afdhal N, Gordon FD.

Clin Gastroenterol Hepatol. 2008 Feb;6(2):255-8. Epub 2008 Jan 9.

2. Cholestatic Jaundice and IgA Nephropathy Induced by OTC Muscle Building Agent Superdrol.

Beata Jasiurkowski MD, et al.

The American Journal of Gastroenterology (2006) 101, 2659-2662;

3. Severe Cholestasis and Renal Failure Associated with the Use of the Designer Steroid Superdrol (Methasteron): A Case Report and Literature Review

John Nasr and Jawad Ahmad

Digestive Diseases and Sciences

4. Metabolism of delta 4-androstene-3beta, 17beta-diol and delta 4-androstene-3alpha, 17beta-diol in vitro.

DORFMAN et al.

J Biol Chem. 1957 Jan;224(1):191-200.

5. On the enzymic conversion of delta 4-3-hydroxy steroids to delta 4-3-ketones.

Ungar et al.

Biochim Biophys Acta. 1957 May;24(2):431.

6. Metabolism of 4-androstene-3,17-beta-diol-3-H3-4-C14 in human subjects.

Kundu et al.

Steroids. 1965 Nov;6(5):543-51.

7. Androgens and erythropoiesis: past and present.

Shahani S, et al.

J Endocrinol Invest. 2009 Sep;32(8):704-16. Epub 2009 Apr 7. Review.

8. Definition of androgens and protein steroids.

Kochakian CD.

Pharmacol Ther B. 1975;1(2):149-77. Review. No abstract available

9. Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining.

Bruusgaard JC et al.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15111-6. Epub 2010 Aug 16.

10. Strength Training and Steroids

Anders Eriksson, et al.

University Medical Dissertations (2006)

11. 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen.

Friedel A, et al.

Toxicol Lett. 2006 Aug 20;165(2):149-55. Epub 2006 Apr 18.

12. Effects of prohormone supplementation in humans: a review.

Ziegenfuss TN, et al.

Can J Appl Physiol. 2002 Dec;27(6):628-46.

Active Steroid Tab: References -

1. Dehydroepiandrosterone: kinetics of metabolism in normal men and women.

Bird CE et al.

J Clin Endocrinol Metab. 1978 Oct;47(4):818-22.

2. In vivo conversion of dehydroisoandrosterone to plasma androstenedione and testosterone in man.

Horton R, et al.

J Clin Endocrinol Metab. 1967 Jan;27(1):79-88.

3. In vitro metabolism of androgens in whole human blood.

Blaquier et al.

Acta Endocrinol (Copenh). 1967 Aug;55(4):697-704. No abstract available.

4. METABOLISM OF ANDROST-4-ENE-3,17-DIONE-4-14C BY RABBIT SKELETAL MUSCLE SUPERNATANT FRACTION. ISOLATION OF 3BETA-HYDROXYANDROST-4-EN-17-ONE-14C AND TESTOSTERONE-14C.

THOMAS et al.

J Biol Chem. 1964 Mar;239:766-72. No abstract available

5. Injectable Pharmacokinetics derived from -

Comparative pharmacokinetics of testosterone enanthate and testosterone cyclohexanecarboxylate as assessed by serum and salivary testosterone levels in normal men.

Schürmeyer T, et al.

Int J Androl. 1984 Jun;7(3):181-7.

6. Blood levels were calculated from conversion percentages derived from the “Active Steroids” tab and based off calculated blood levels of administered steroids on the “Oral Delivery” tab.

Oral Delivery Tab: References -

1. Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

Porter et al.

Nat Rev Drug Discov. 2007 Mar;6(3):231-48. Review

2. Effect of oily vehicles on absorption of mepitiostane by the lymphatic system in rats.

Ichihashi et al.

J Pharm Pharmacol. 1992 Jul;44(7):560-4

3. Clinical studies with oral lipid based formulations of poorly soluble compounds.

Fatouros et al.

Ther Clin Risk Manag. 2007 Aug;3(4):591-604.

4. Lipid--an emerging platform for oral delivery of drugs with poor bioavailability.

Chakraborty et al.

Eur J Pharm Biopharm. 2009 Sep;73(1):1-15. Epub 2009 Jun 6.

5. Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies.

Pouton et al.

Adv Drug Deliv Rev. 2008 Mar 17;60(6):625-37. Epub 2007 Nov 4. Review

6. Relationships between the molecular structures and emulsification properties of edible oils.

Masami et al.

Biosci. Biotech. Biochem 58 (7), 1258-1261, 1994

7. Absolute bioavailability of testosterone after oral administration of testosterone-undecanoate and testosterone.

Täuber U, Schröder K, Düsterberg B, Matthes H.

Eur J Drug Metab Pharmacokinet. 1986 Apr-Jun;11(2):145-9

8. Lymphatic absorption and metabolism of orally administered testosterone undecanoate in man.

Horst HJ, et al.

Klin Wochenschr. 1976 Sep 15;54(18):875-9.

9. The effect of drug lipophilicity and lipid vehicles on the lymphatic absorption of various testosterone esters

T. Noguchia, et al

International Journal of Pharmaceutics Volume 24, Issues 2-3, May 1985, Pages 173-184

10. Self-emulsifying drug delivery systems: an approach to enhance oral bioavailability.

Kohli et al.

Drug Discov Today. 2010 Nov;15(21-22):958-65. Epub 2010 Aug 17.

11. Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs.

Gershanik et al.

Eur J Pharm Biopharm. 2000 Jul;50(1):179-88.

12. Self-Emulsifying Drug Delivery Systems: Strategy for improving oral delivery of poorly water soluble drugs.

Jing et al.

Current Drug Therapy, 2007, 2, 85-9

13. Oral bioavailability enhancement of exemestane from self-microemulsifying drug delivery system (SMEDDS).

Singh et al.

AAPS PharmSciTech. 2009;10(3):906-16. Epub 2009 Jul 17

14. Enhancing intestinal drug solubilisation using lipid-based delivery systems.

Porter et al.

Adv Drug Deliv Rev. 2008 Mar 17;60(6):673-91. Epub 2007 Nov 7.

15. Phospholipids and lipid-based formulations in oral drug delivery.

Fricker et al.

Pharm Res. 2010 Aug;27(8):1469-86. Epub 2010 Apr 22. Review

16. Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid.

Kantola T, Kivistö KT, Neuvonen PJ.

Clin Pharmacol Ther. 1998 Apr;63(4):397-402.

17. Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.

Schmiedlin-Ren P, et al.

Drug Metab Dispos. 1997 Nov;25(11):1228-33.

18. Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds

Ping-Chuen Ho et al.

J Pharm Pharmaceut Sci 4(3):217-227, 2001

19. Can grapefruit juice influence ethinylestradiol bioavailability?

Weber A, et al.

Contraception. 1996 Jan;53(1):41-7.

20. Grapefruit juice-drug interactions. 1998.

Bailey DG, Malcolm J, Arnold O, Spence JD.

Br J Clin Pharmacol. 2004 Dec;58(7):S831-40; discussion S841-3.

21. Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17 beta-estradiol.

Schubert W, Eriksson U, Edgar B, Cullberg G, Hedner T.

Eur J Drug Metab Pharmacokinet. 1995 Jul-Sep;20(3):219-24.

22. Inhibition of estrone sulfatase in human liver microsomes by quercetin and other flavonoids.

Huang Z, et al.

J Steroid Biochem Mol Biol. 1997 Sep-Oct;63(1-3):9-15.

23. Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction.

Li P, et al.

Drug Metab Dispos. 2007 Jul;35(7):1203-8. Epub 2007 Apr 23.

24. Esterase inhibition attribute of grapefruit juice leading to a new drug interaction.

Li P, Callery PS, Gan LS, Balani SK.

Drug Metab Dispos. 2007 Jul;35(7):1023-31. Epub 2007 Mar 28.

25. Lymphatic transport of Methylnortestosterone undecanoate (MU) and the bioavailability of methylnortestosterone are highly sensitive to the mass of coadministered lipid after oral administration of MU.

White L, et al.

J Pharmacol Exp Ther. 2009 Nov;331(2):700-9. Epub 2009 Aug 20.

26. “Standard pill” data was calculated from below mentioned references. The “Liqua-Vade” value was calculated using ‘standard pills’ data as a reference point. Blood levels where enhanced according to lipophilic delivery (3x), SEDDS (3x), and grapefruit drug interaction (15x) – for an average effect of 25x over standard pills with a maximum limit of 85% absorption and 75% bioavailability.

The effects of oral dehydroepiandrosterone on endocrine-metabolic parameters in postmenopausal women.

Mortola JF, et al.

J Clin Endocrinol Metab. 1990 Sep;71(3):696-704.

Absolute bioavailability of testosterone after oral administration of testosterone-undecanoate and testosterone.

Täuber U, Schröder K, Düsterberg B, Matthes H.

Eur J Drug Metab Pharmacokinet. 1986 Apr-Jun;11(2):145-9

Androstenedione does not stimulate muscle protein in young healthy men.

Rasmussen BB, et al.

J Clin Endocrinol Metab. 2000 Jan;85(1):55-9.

Effect of oral androstenedione on serum testosterone and adaptations to resistance training in young men: a randomized controlled trial.

King DS, et al.

JAMA. 1999 Jun 2;281(21):2020-8.

Quantitative determination of metabolic products of 19-norandrostenediol in human plasma using gas chromatography/mass spectrometry.

Schrader Y, et al.

Drug Metab Dispos. 2006 Aug;34(8):1328-35. Epub 2006 May 19.

Oral androstenedione administration and serum testosterone concentrations in young men.

Leder BZ, et al

JAMA. 2000 Feb 9;283(6):779-82.

Effects of precursors on serum testosterone concentrations and adaptations to resistance training in young men.

Brown GA, et al.

Int J Sport Nutr Exerc Metab. 2000 Sep;10(3):340-59.

Comparative pharmacokinetics of testosterone enanthate and testosterone cyclohexanecarboxylate as assessed by serum and salivary testosterone levels in normal men.

Schürmeyer T, et al.

Int J Androl. 1984 Jun;7(3):181-7.

Lymphatic absorption and metabolism of orally administered testosterone undecanoate in man.

Horst HJ, et al.

Klin Wochenschr. 1976 Sep 15;54(18):875-9.

Oral testosterone, a reappraisal.

Daggett PR, et al.

Horm Res. 1978;9(3):121-9.

Bioavailability of oral testosterone in males.

Frey H, et al.

Eur J Clin Pharmacol. 1979 Nov;16(5):345-9.

Therapeutic effectiveness of oral testosterone.

Johnsen SG, et al.

Lancet. 1974 Dec 21;2(7895):1473-5.

Oral testosterone in oil: pharmacokinetic effects of 5alpha reduction by finasteride or dutasteride and food intake in men.

Amory JK, et al.

J Androl. 2006 Jan-Feb;27(1):72-8.

Oral testosterone in oil plus dutasteride in men: a pharmacokinetic study.

Amory JK, Bremner WJ.

J Clin Endocrinol Metab. 2005 May;90(5):2610-7. Epub 2005 Feb 15.

Pharmacokinetics and pharmacodynamics of oral testosterone enanthate plus dutasteride for 4 weeks in normal men: implications for male hormonal contraception.

Amory JK, et al.

2008 May-Jun;29(3):260-71. Epub 2007 Nov 28.ST.