Phenibut Powder (50 grams)

Phenibut (beta-phenyl- gamma-aminobutyric acid) is a derivative of the neurotransmitter GABA that crosses the blood-brain barrier [1]. It was developed in Russia, and there it has been used clinically since the 1960's for a range of purposes. Phenibut has both nootropic and anxiolytic (anxiety-reducing) properties, and it is commonly compared to diazepam (Valium), baclofen, and piracetam, and it has similarities to and differences from all of these substances.

Structurally, phenibut is similar to GABA, baclofen (p-Cl-phenibut), and beta-phenylethylamine (PEA). GABA is the primary inhibitory neurotransmitter in the brain. The addition of the phenyl ring to GABA allows the compound to more easily cross the blood-brain barrier, but also changes its activity profile [1-2]. Baclofen is a drug commonly used in studies on GABA(B) receptors, and also clinically used to treat severe spasticity of cerebral origin [3]. PEA is a naturally occuring biogenic amine which is similar in structure to amphetamine, and like amphetamine, it is a stimulant that causes the release of dopamine, and also promotes anxiety in high enough amounts.

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Customer Reviews for Phenibut Powder (50 grams)

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relax By: christopher

Review posted on: Tue Nov 13 16:55:07 -0500 2007

this stuff is the best for relaxing feelings, start with 500mgs. though and then work your way up, and set aside at least 8-10 hours to sleep. you will feel relaxed, focused, and strong sense of well being. it should not make you tired right away but when you get into larger doses watch out, about 2 or 3 hours after dosing......you're bed is going to look awful nice (or someone else's bed).

potent mind relaxation By: Justin

Review posted on: Tue Nov 13 16:54:56 -0500 2007

Works really well for a nice, relaxing evening at 750mg - 1.5 grams. Depends on your tolerance. Be careful not to use it too often or you will build a tolerance VERY quickly! Mixes nice with a few cocktails (not in the drink). Try it sublingual for a much faster delivery.