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Rating: 5.0/5 (2 votes cast)
NA-RALA 100 GRAMS (100 gm)
Manufacturered By: NutraPlanet
Shipping Methods USPS (APO/FPO, PO Box, International, Domestic), FedEx Ground/Express (Domestic, International)
Na-RALA: The Next Generation Antioxidant
- 30% stronger than K-RALA and is a free-flowing powder
- 15g Na-RALA = 20g K-RALA
- 57g Na-RALA = 100 g K-RALA
In 2003, GeroNova launched the first stabilized R-lipoic acid (RLA) containing dietary ingredient into the nutraceutical market: K-RALA (Potassium RLA).
The pure potassium salt is unstable and had to be supported on silica and MCC after de-polymerization to make it suitable for tablets and capsules.
The additional processing raised the cost of an already expensive raw material (RLA), and could only be offered with a 40% active load.
Na-RALA: The Next Generation RALA
Bio-EnhancedTM Na-RALA is a 70% active R-lipoic acid powder is stable, extremely low (<2.0 %) in insoluble polymer and offers an innovative solution for capsules, tablets and powdered drink mixes.
Bio-EnhancedTM Na-RALA is completely water soluble.
Bio-EnhancedTM Na-RALA is significantly more bioavailable than R-lipoic acid (RLA).
· 1000mg (1gram) RLA reaches a maximum concentration (Cmax) of 1.1ug/ml in human plasma
· 100mg (0.1gram) Bio-Enhanced Na-RALA reaches a Cmax of 2.3ug/ml
· On a weight basis Bio-Enhanced Na-RALA reaches a Cmax 21 times higher than RLA.
Specifications:
Bio-EnhancedTM Na-RALA powder is an off-white to yellowish powder, with 70% active R-lipoic acid.
Bio-EnhancedTM Na-RALA powder is soluble in water. 1 g dissolves in 50 ml water at room temperature.
Bio-EnhancedTM Na-RALA powder melts at 240° ~ 250° C (with decomposition beginning at (~210° C).
Bio-EnhancedTM Na-RALA powder is free flowing, heat stable up to 85° C and ready for blending with excipients.
Advantages:
Increased stability:
Bio-EnhancedTM Na-RALA requires no refrigeration and has a shelf life of at least 3 years without polymerization. Solid R-Lipoic Acid is prone to quickly polymerize upon exposure to heat, light, and moisture.
Increased Solubility:
cleanly soluble in water, whereas RLA is poorly soluble and K-RALA can only be dispersed because of the insoluble excipients.
Reduced Solvent Residues:
due to the low melting point of the lipoic acid crystalline structure, there is a tendency for RLA to hold on to high amounts of cyclohexane, ethyl acetate or toluene.
The additional processing necessary to make Bio-EnhancedTM Na-RALA removes the residual solvents.
To deliver a 100 mg active dose of RLA required 250 mg K-RALA-40%
To deliver a 100 mg active dose of RLA requires 143 mg Na-RALA-70%
Certificate of Analysis
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21x Stronger than R-ALA By: Robert
Review posted on: Tue Nov 13 16:55:11 -0500 2007
21x Stronger than R-ALA! 3x a day 1/2 hour before meals. Dbl dose immediately after workout.
Take Acetyl L-Carnitine with - cause each enhance the other. (the Acetyl L-Carnitine should be taken as a transdermal or sublingual though - your body will only absorb 20% or so otherwise, why waste product and cash?)
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