Achilles (120 Caps)
Manufactured By: Antaeus Labs
USPS (APO/FPO, PO Box, International, Domestic), FedEx Ground/Express (Domestic, International)
Antaeus Labs' Achilles: Ultimate Tendon Support!
By combining cutting-edge pharmaceutical-grade ingredients with tried-and-tested high-quality herbal extracts, new Achilles from Antaeus Labs brings you the most advanced joint-support formula on the market!
Every hero has a weakness. For many weightlifters and bodybuilders this is their joints. Tendons and ligaments bear the brunt of punishing weight-lifting sessions, commonly becoming inflamed and sore.
The connective tissue just can't keep up with the heavier and heavier weights lifted week after week.
Niggling pains become chronic injuries, often requiring a forced rest, a change of routine or the permanent dropping of some exercises altogether.
40 years of scientific research has established Palmitoylethanolamide (PEA) as one of the most important endogenous painkilling and anti-inflammatory compounds.
Brazilian traditional medicine uses H. aphrodisiaca for, among other things, muscle and bone weakness – use that has been borne out recently when a study found that H. aphrodisiaca-treated trained rats had stronger tendons that could take a bigger load and more stress than untreated trained rats. 
“H. aphrodisiaca associated with endurance training contributed to more efficient remodeling of the extracellular matrix, resulting in more resistant tendons to support high loads from intense muscle contraction. These findings suggest that H. aphrodisiaca infusion is a potential aid to optimize tendon remodeling in athletes.” 
Kirenol The plant Xi Xian Cao (Siegesbeckia orientalis) has been used for centuries in traditional chinese medicine (TCM) for its anti-inflammatory properties. One constituent of Siegesbeckia is Kirenol – which has recently been discovered to be a potent anti-inflammatory that also suppressed joint inflammation and inhibited cartilage and bone destruction in a rat model of arthritis. 
Asthisamharaka (Cissus Quadrangularis) is another herb that has been used for centuries in Ayurvedic medicine to heal broken bones and injured ligaments and tendons.  Numerous studies show that Cissus is anti-osteoporotic and pro-osteogenic, and it’s long been a staple in the arsenal of athletes and bodybuilders with joint problems. 
Zingiber Zerumbet is a species of ginger, the rhizome (root) of which has been used traditionally throughout Southeast Asia to treat pain and inflammation. Recent studies have demonstrated antinociceptive, anti-inflammatory, and antioxidant properties.  In addition to containing molecules such as 6-gingerol, which are very well-known anti-inflammatory modulators, some of the phytochemical constituents that make up Zingiber Zerumbet have been found to be potent histone deacetylase (HDAC) inhibitors.  Several studies have recently concluded that HDAC inhibition can reduce joint inflammation and protect cartilage. 
“In conclusion, inhibition of HDAC prevents joint inflammation and cartilage and bone destruction in experimental arthritis.” 
“HDAC inhibitors may therefore be novel chondroprotective therapeutic agents in arthritis by virtue of their ability to inhibit the expression of destructive metalloproteinases by chondrocytes.” 
Achilles Q&A: A Discussion Between NutraPlanet & Antaeus Labs:
NutraPlanet: What prompted you to release a joint supplement?
Antaeus Labs: I think it's a combination of the exciting research that was coming out about some of the ingredients that we went on to include, and a desire to help people recover from injuries. I felt a multi-faceted approach should yield better results than people are experiencing with some of the products currently on the market.
NutraPlanet: You want to... help people?
Antaeus Labs: Of course! Sports and weightlifting soft-tissue injuries are incredibly common. Anything we can do to help minimize the time spent recuperating - or in pain - is well worth doing. It has a real impact on people's quality of life.
NutraPlanet: So tell us a little about your formulation.
Antaeus Labs: It has several different naturally-occurring anti-inflammatory, pain-modulating, and anti-oxidant ingredients - though most of them are probably unfamiliar to most consumers. Two that people may be familiar with are Palmitoylethanolamide (PEA) and Cissus Quadrangularis. Cissus is a very popular joint supplement, and PEA is an extremely well-studied PPAR-alpha agonist with combined anti-inflammatory and pain-reducing properties.
NutraPlanet: The dose of Cissus you use seems low, compared to some other products?
Antaeus Labs: Indeed it is, deliberately so. There are a number of peer-reviewed studies on Cissus, almost all relating to its effects on bone health and regeneration, and as far as I know none of them demonstrating positive effects on tendon or ligament healing. Nevertheless, it's probably the second-most popular joint supplement on the market, and some people swear by it. We've included it at a moderate dose, to limit the number of caps people have to take to a reasonable number. Of course, if people want to take a higher dose of cissus than is found in Achilles it's easy enough to "top-up" with a cissus-only product.
NutraPlanet: The cissus isn't standardized for ketosterone content?
Antaeus Labs: I've seen no evidence that ketosterones are the active constituent of the cissus extract, so to standardise for them could in fact make the extract less potent.
NutraPlanet: What is the optimal dose of Achilles, and can it be increased if required?
Antaeus Labs: The recommended dose of Achilles is four capsules per day; ideally, two in the morning & two in the evening, with meals. Four capsules contains the optimal dose for most of the ingredients that this formula contains. The major exception would be the Cissus extract, where the optimal dose seems to be in the 2200-3000mg/day range.
NutraPlanet: How long after people start taking it should they expect to see an improvement?
Antaeus Labs: The anti-inflammatory effects should come on fast, and should be noticeable within hours. Actual tendon/ligament healing takes weeks - so people suffering from acute injuries or overuse injuries should use the product for at least a month, while refraining from any exercise which would place stress on the affected tendon, joint or ligament.
NutraPlanet: Is it for acute injuries or only for chronic complaints?
Antaeus Labs: I think that people suffering from acute injuries should first see a doctor - preferably an orthopedic specialist. If the injury is nothing serious, this product might help them recover more quickly and might alleviate some pain. If the injury is severe, they might need heavy-duty painkillers or surgical treatment.
NutraPlanet: Should this be used instead of, or as well as RICE (Rest, Ice, Compression, Elevation) or MEAT (Movement, Exercise, Analgesics, Treatments)?
Antaeus Labs: This product can perhaps speed up the healing process & alleviate discomfort - but it's no panacea. It can't take the place of RICE or MEAT. It would be better to use it along with them.
NutraPlanet: Can it be used in conjunction with NSAIDs?
Antaeus Labs: There should be no significant interactions between Ibuprofen & any component in Achilles. Palmitoylethanolamide might improve the efficacy of Acetaminophen. (Between us, this may be due to the fact that PEA is an endocannabinoid-inducer, and Acetaminophen is essentially an endocannabinoid reuptake inhibitor. PMID: 20035773) The short answer to this question is yes: You can use Achilles along with your OTC NSAID.
NutraPlanet: "Is there any additional benefit to our customers stacking Achilles with another joint supplement, like Joint Force, Joint Fixx, or Skeletal Balm?"
Antaeus Labs: "I believe that it stacks remarkably well with every other joint-support product on the market. JointForce, Joint Fixx, & SuperCissus are all excellent ideas for a stack.
 Verme JL, Fu J, Astarita G, Rana GL, Russo R, Calignano A, et al. The Nuclear Receptor Peroxisome Proliferator-Activated Receptor-α Mediates the Anti-Inflammatory Actions of Palmitoylethanolamide. Mol Pharmacol. 2005 Jan 1;67(1):15–9.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Write a review and share your thoughts with other customers.
Very good By: Derek
Review posted on: 2013-02-08 11:18:57 -0500
I have bad knees and shoulders due to years in the military. I have tried multiple joint supplements and Cissus is an awesome support supplement. Achilles and that at an affective dose and more. My knees and shoulders don't pop in the morning. My knees aren't sore after squats. Shoulders feel great after working out. This is my go to joint supplement now on.