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Vapor XT by Advanced Muscle Science
Vapor-XT provides a simple, yet powerful blend of ingredients designed to fill this void. Vapor-XT does not hide the ingredients behind some veil of secrecy known as the proprietary blend. It provides a simple yet targeted approach with key ingredients in precise amounts so results are delivered.
The first of three key ingredients in Vapor-XT is an ingredient known by the name Halostachine™. Halostachine, also known as N-methylphenylethanolamine, is a potent beta adrenergic agonist similar in structure and activity to ephedrine. Beta-receptors, particularly Beta-3 play an integral role in stimulating the release of fatty acids from the adipocytes. This is a key step in the thermogenic pathways and one that must be invoked for fat loss to occur.
Halostachine is found naturally in rye grass and also produced exogenously in mammals and standardized from the plant Halostachys caspica. Furthermore, it is a natural metabolite of phenylethylamine, which is found naturally in cocoa beans. Halostachine has pharmacological action similar to ephedrine but is slightly less potent and believed to be much safer. Halostachine is less toxic than ephedrine, with an LD50 twice that of ephedrine, 500 mg/kg ip vs 242 mg/kg sp which gives an indication of the relative toxicity of this ingredient compared to other similar products. Anecdotal testing of Halostachine suggests that it is actually more effective than ephedrine, giving it a much better therapeutic index (efficacious dose)/(toxic dose). A paper by Shannn, Cone and Yousefnejad demonstrated no significant increases in heart rate with Halostachine administration - even when administered intravenously at doses of several multiples of those proposed for supplemental use.
The other two key ingredients found in new Vapor-XT are caffeine and white willow bark, two of the original key components in the original ECA stack.
Anyone that has ever ingested caffeine knows its effects, increased energy, increased thermogenesis, etc… The effects of Caffeine are quite frankly, common knowledge so let’s just take a peek at some key pertinent studies. The science behind caffeine is well documented and its street credibility undeniable. Looking specifically at thermogenesis, a study just published by Belza looked at the acute thermogenic response to caffeine ingestion. Thermogenesis, the key indicator of overall metabolic rate, was measured for a period of 4-hrs after the ingestion of caffeine. Results showed a six percent greater level of thermogenesis over the course of the treatment period. This kind of elevation is certainly of key interest to those waging war on unwanted bodyfat.
Additionally caffeine has shown to be extremely beneficial on exercise performance and maximizing intense training. In one study looking at the ingestion of caffeine on peak power output, caffeine supplementation increased Peak Power output by 6.7%. These 14 individuals consumed 250 mg of caffeine prior to exercise. In terms of the raw data, Peak Power in the placebo group was only 903.7 watts whereas after caffeine ingestion it was 964 watts. Imagine all those extra fat burning reps enhanced by caffeine ingestion.
The last ingredient in this thermogenic trio is white willow bark as a source for salicin which converts to salicylic acid in the body. This particular ingredient by itself has never been shown to have any thermogenic activity. So by itself it probably wouldn’t prove to be overly useful in shedding bodyfat. However, when combined with other agents that have thermogenic activity its effects are pronounced. White willow bark, through certain pathways involving prostaglandins and other messaging systems, may help to increase and extend the thermogenic activity of the other compounds in the formula.
So there you have it. Vapor-XT represents a critical shift in the way you’ve looked at thermogenics. Delivering two highly-powerful thermogenics, coupled with a compound designed to extend the physiological life of the product and help keep fat burning going strong. Simple, powerful and effective –Vapor-XT.
References:
1. Liapakis G, Chan WC, Papadokostaki M, Javitch JA. Synergistic contributions of the functional groups of epinephrine to its affinity and efficacy at the beta2 adrenergic receptor. Mol Pharmacol. 2004 May;65(5):1181-90.
2. Fang Y, Ferrie AM. Label-free optical biosensor for ligand-directed functional selectivity acting on beta(2) adrenoceptor in living cells. FEBS Lett. 2008 Mar 5;582(5):558-64.
3. Manske & Holmes. The Alkaloids, Volume III. Chapter 22, 1953.
